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Information × Registration Number 0215U000275, 0110U000403 , R & D reports Title Investigation of reparative effect of cord blood low-molecular fraction on cryopreserved cells popup.stage_title Head Gulevsky Alexandr Kirillovich, Registration Date 05-02-2015 Organization Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of the Ukraine popup.description2 Study Purpose: To argue the prospective of addition of the low-molecular fraction (below 5 kDa) from the cattle cord blood to rehabilitating media to improve the functional activity of human donor blood leukocytes after hypothermic storage. Study Object: functional state of human donor blood leukocytes subjected to hypothermic storage after incubation in media containing the low-molecular fraction. Methods: ultrafiltration, biochemical, spectrophotometric, immunologic methods, light microscopy. Study Results: It was found that the cord blood low-molecular fraction below 5 kDa and the reference drug Actovegin in rehabilitating media stimulated the functional activity and the capacity for generation of active oxygen species of donor blood leukocytes after hypothermic storage. The data obtained can become a basis for further investigations of influence of the low-molecular fraction as a part of media on recovery of the functional state of cryopreserved leukocytes. Product Description popup.authors Абакумова О.С. Горіна О.Л. Гулевський О.К. Моісєєва Н.М. Нікольченко А.Ю. Трифонова Г.В. Щенявський І.Й. popup.nrat_date 2020-04-02 Close