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Information × Registration Number 0215U000360, 0114U003143 , R & D reports Title To find out new predictors of the course of BCR-ABL negative chronic myeloproliferative neoplasms and to develop principles of risk adapted therapy popup.stage_title Head Maslyak Zvenyslava Volodymyrivna, Registration Date 10-02-2015 Organization LVIV RESEARCH INSTITUTE OF BLOOD PATHOLOGY AND TRANSFUSIONAL MEDICINE popup.description2 In the process of investigation a group of patients with chronic myeloproliferative neoplasms was formed, which included patients with idiopathic and secondary myelofibrosis, essential thrombocythemia and polycythemia vera. Patients were examined using clinical and additional laboratory methods, including specific cytogenetic and molecular genetic techniques. Based on a comprehensive study of hematopoietic cells karyotype, histological changes in the bone marrow, levels of proinflammatory and proangiogenic cytokines, JAK2 mutations in the course of BCR-ABL negative chronic myeloproliferative neoplasms, a set of differential diagnostic criteria for each nosology in this group are to be determined.54815481 Product Description popup.authors Бойко Ольга Ігорівна Везденко Лідія Орестівна Виговська Ярослава Іллівна Даниш Ольга Йосипівна Дяків Г. Л. Зозуля Тетяна Омелянівна Кароль Ю. С. Котлярчук Констянтин Богданович Лозинський Ростислав Юрійович Мельник М. І. Сімонова Мар'яна Іванівна Тераз С. С. popup.nrat_date 2020-04-02 Close