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Information × Registration Number 0215U001044, 0111U010128 , R & D reports Title To study the mechanisms of pathological changes of the circulatory system and their impact on physical activity in patients with bronchial asthma popup.stage_title Head Feshchenko Yuriy Ivanovich, Registration Date 14-01-2015 Organization SO "National institute of phthisiology and pulmonology named after F. G. Yanovsky NAMS of Ukraine" popup.description2 Object: 120 patients with bronchial asthma. Aim: improving quality of life in patients with asthma by examining violations of the functional state of the cardiorespiratory system in a graduated exercise and develop ways of preventing their progression. Methods: clinical, functional and statistical. Was found that in mild persistent disease course maximum level of accomplishment load decreased in comparison with the group of healthy on 12.5 % during exacerbation and on 3.5% in remission. In patients with moderate severity of disease exacerbation in its level of accomplishment load had decreased by 47.5 % and 25.5 % respectively. A new method of prevention decline in physical activity patients with bronchial asthma using drugs on the basis of ginkgolides and bilobalides that allows significantly to increase the level of execution of works from 68.2 % to 95.9 %, to improve physical activity from 72.2 % to 92.6 %, to increase the oxygen cost of work performed from 69.0 % to 96.6 %, and to improve performance in oxygen consumption from 75.2 % to 98.5 %, and significantly to improve the efficiency of the cardio - vascular system when performing exercise, which was confirmed by normalization of maximum heart rate at the height of physical activity (HR) to (149,4 ± 2,2) beats/min to (113,4 ± 2,7) beats/min, a significant increase in oxygen pulse (VO2/HR) of (7,0 ± 0,3) % to (9,2 ± 0,2) %, a decrease in chronotropic response heart, increase HR/Vkg of (6,2 ± 0,2) beats/min/W to (8,9 ± 0,2) beats/min/W. Sphere of application - рulmonology Product Description popup.authors Адамчук Олександр Ігорович Бегоулєва Жанна Борисівна Бриньова Тетяна Іванівна Канарський Олександр Анатолійович Крилач Олена Ігорівна Курик Леся Михайлівна Меренкова Евгенія Олександрівна Пархоменко Наталія Володимирівна Примушко Наталія Андріівна РолікЛюдмила Володимирівна Сінгаєвський Мирослав Богданович Турчина Інна Петрівна Фещенко Юрій Іванович popup.nrat_date 2020-04-02 Close