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Information × Registration Number 0215U001242, 0114U007087 , R & D reports Title The role of Ca2+-transport systems in the regulation of substrate oxidation in situ in the secretory cells of exocrine glands in different functional states of the organism. popup.stage_title Head Manko Volodymyr Vasylyovych, Registration Date 03-02-2015 Organization Ivan Franko National University of Lviv popup.description2 The object of the investigation: energy supply of the secretory cells of exocrine glands. Subject of the investigation: the system of regulation of mitochondrial respiration of secretory cells. The aim of the project: establishment the role of intracellular Ca2+ tranport systems in the regulation of mitochondrial respiration of secretory cells in conditions close to native in different functional states of the body. Figuring features of the endoplasmic-mitochondrial Ca2+ functional unit. It was shown a fact of hormone cholecystokinin activation of mitochondrial respiration in pancreas and clarified the characteristics of this regulation, in particular as a result of alcohol (ethanol) influence. Identified the influence of mitochondrial RYRs on the intensity of mitochondrial respiration in hepatocytes. The influence of taurine, often used as a food additive for bioenergetics on physiological characteristics (behavior, blood parameters), the activity of enzymes aspartate aminotransferase, alanine aminotransferase, lactate dehydrogenase and mitochondrial respiration in different tissues. Product Description popup.authors Іккерт Оксана Володимирівна Бабський Андрій Мирославович Великопольська Ольга Юріївна Манько Богдан Олексійович Мерлавський Володимир Михайлович popup.nrat_date 2020-04-02 Close