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Information × Registration Number 0215U001377, 0111U010516 , R & D reports Title Multicomponent cyclization reactions involving carbonyl compounds and binucleophile reagents - a direct pathway to analogs of biologically active natural compounds popup.stage_title Head Orlov Valerii, Registration Date 16-02-2015 Organization Kharkov National University named after V.N. Karazin popup.description2 The object of investigation - multicomponent cyclization reactions involving carbonyl compounds and binucleophile reagents - a direct pathway to analogs of biologically active natural compounds; heterocyclization reactions of different unsaturated carbonyl compounds with nitrogen-containing nucleophiles; three-component condensation of arylglyoxals, substituted thioureas and 1,3 dimethylbarbituric acid; 4-chloroalkyl-3,4-dihydropyrimidines; reactions of 4 oksobenz[1,3-f]oksazyn perchlorate and ?-aminoazoles; properties of 3 hydroxychromone derivatives. The aim of the work is to determine the regioselectivity of reactions of chosen unsaturated carbonyl compounds with nitrogen-containing nucleophiles; investigation of fluorescent properties of 3 hydroxychromone derivatives. New cyclocondensation reactions of different unsaturated carbonyl compounds (chalcones, aroylacrilic acids) with nitrogen-containing nucleophiles are investigated. The new 3 hydroxychromone derivatives, wich, by high quantum output of fluorescence and effective proton phototransfer in excited state, are percpective for making up of new effective fluorescent probes. Product Description popup.authors Власенко С. Воробьева Н. Десенко С. Дорошенко А. Колос Н. Колосов М. Котляр В. Кулик О. Ліпсон В. Лебединець Т. Орлов В. Папонов Б. Свечкарєв Д. Сидоренко Д. Чечіна Н. Чумак А. popup.nrat_date 2020-04-02 Close