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Registration Number

0215U001391, 0112U000826 , R & D reports

Title

Search markers to improve standardization of of medicinal plants families Compositae and Lamiaceae in plant mixtures

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Head

Tsurkan Alexandr,

Registration Date

26-02-2015

Organization

State Establishment "Institute of Pharmacology and Toxicology National Academy of Medical Science of Ukraine"

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Aim: Search among biologically active substances of plant families Compositae and Lamiaceae markers for identification and quantification of components of medicinal plant mixtures and herbal remedies. Development of advanced multicomponent herbal remedies. The objects of research - medicinal herbs: Mentha piperita L., Chamomilla recutita L., Calendula officinalis L., Achillea millefolium L., Rosmarinus officinalis L., Leonurus cardiac L., Cichorium intybus L., Prunella vulgaris L. Methods: chromatographic (TLC, HPLC, HRH), UV spectrophotometry, chemical. To address one of the topical problems of modern pharmacy - standardization of multicomponent herbal remedies presents a new methodology for the analysis of plant mixtures based on use marker compounds. With the application of this methodology for the first time a set of analytical methods for qualitative and quantitative standards to potential and existing multi-herbal remedies these herbal components: Mentha piperita L., Chamomilla recutita L., Calendula officinalis L., Achillea millefolium L., Rosmarinus officinalis L., Leonurus cardiac L., Cichorium intybus L., Prunella vulgaris L., etc. The developed method tested on registered pharmaceutical market of Ukraine multicomponent herbal remedies.

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Голембіовська Олена Ігорівна
Гудзенко Андрій Вікторович
Делян Євген Петрович
Джан Тетяна Віталіївна
Зоценко Людмила Олексіївна
Ковальчук Тетяна Василівна
Колядич Олена Павлівна
Семенченко Ольга Михайлівна
Ющишина Ольга Володимирівна

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2020-04-02