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Information × Registration Number 0215U001607, 0112U000785 , R & D reports Title Development of new methods of prediction and prevention of cardiovascular events in patients with osteoarthritis of the metabolic syndrome popup.stage_title Head Grishyna Olena Igorivna, Registration Date 31-03-2015 Organization The Mechnikov Research Institute of microbiology and immunology at Kharciv popup.description2 The object of study - patients with osteoarthritis (OA) and metabolic syndrome (MS) and cardiovascular disease (CVD). Objective: To study the role of the immune system and the dynamics of the inductors of inflammation in the formation of the structure and polymorbidity of cardiovascular complications in patients with OA with MS and develop differentiated schemes to prevent them on this basis. Methods of research - epidemiological, clinical, instrumental, biochemical, immunological. Results and novelty - the first time studied the state of cellular and humoral immunity, the content of tumor necrosis factor alpha, interleukin-6, monocyte chemotactic factor-1 in patients with OA of MS depending on the progression of CVD risk on a scale Prospective Cardiovascular Munster (PROCAM) and hemodynamic . Their role in the implementation of the pathological process and differentiation of prognostic significance. Developed a method for predicting the progression of OA. Pathogenetically substantiated scheme of CVD prevention in patients with OA of the MS. Product Description popup.authors Іванченко Жанна Брониславівна Бабінець Ольга Михайлівна Волянська Наталія Петрівна Гіржанова Інна Владленівна Давидова Тетяна Володимирівна Довга Інна Миколаївна Коляда Олег Миколайович Менкус Олена Валеріївна Мурадян Ольга Василівна Чернявський Віталій Ілліч popup.nrat_date 2020-04-02 Close