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Information × Registration Number 0215U003118, 0114U001641 , R & D reports Title Making and investigation new nanobiomaterials based on recobimbinant single-chain antibodies and nanostructured substrates for nanobiosensor immunodiagnosis. Step 5. Development of analityc applying methods of nanobiosensors based on developed nanobiomaterials. popup.stage_title Head Lebyedyeva Tetyana Stanislavivna, Registration Date 15-01-2015 Organization V.M.Glushkov Institute of Cubernetics of NASU popup.description2 First create a dialog program to calculate the reflection curves and sensitivity of nanostructured multilayer sensor structures with porous waveguide layer with built-in routines for calculating the effective refractive index of the porous layer on the effective medium model of the Maxwell-Garnett. Developed a new type of sensor technology structures with an intermediate layer of niobium anodic oxide. This technology provides uniformity Al underlayer thickness of 10-20 nm, as well as the chemical stability of the sensors at biosensor research. Clarified optimized composition of nanostructured multilayer substrates touch to work with created at the Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine recombinant immunoreagents. It was shown that the recombinant surface protein analogue Staphylococcus aureus (protein SPA) as part of a fusion protein SPA-Cys efficiently mobilized on a nanostructured substrate surface based porous anodic aluminum oxide films of nanostructured gold nanometer thickness, while retaining the binding properties with respect to human immunoglobulin. Together with the Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine developed methods of using recombinant immunoreagents in optical waveguide sensors with a metal underlayer with nanostructured sensor substrates. Product Description popup.authors Прімін Михайло Андрійович Шпильовий Павло Борисович popup.nrat_date 2020-04-02 Close