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Information × Registration Number 0215U003227, 0114U002848 , R & D reports Title The comparative study of genetic predisposition to the development of breast cancer in women, which were exposed to ionizing radiation as a result of the Chernobyl accident. popup.stage_title Head Klymenko Sergij, Доктор медичних наук Registration Date 21-01-2015 Organization State institution "National research centеr for radiation medicine of the National academy of medical sciences of Ukraine " popup.description2 Оbjectives - women with breast cancer in , which were exposed to ionizing radiation as a result of the Chernobyl accident, women with the spontaneous breast cancer. Purpose - to work out methods for determining genetic polymorphisms rs2981582 of the FGFR2 gene, rs3803662 of the TNRC9 gene, rs889312 of the MAP3K1 gene, rs12443621 of the TN2981582RC9 gene and rs3817198 of the LSP1 gene. Methods - medical-genetical consultation,molecular genetical methods, mathematic statistics.Methods for determination of the genetic polymorphisms rs2981582 of the FGFR2 gene, rs3803662 of the TNRC9 gene, rs889312 of the MAP3K1 gene, rs12443621 of the TN2981582RC9 gene and rs3817198 of the LSP1 gene were worked out. It's were found that the leading risk factors for breast cancer are the age under 50 years, reproductive factors (early menarche, breast-feeding up to three months) and a family history of breast cancer or ovarian cancer. Product Description popup.authors Cефанович Г.В. Бичкова Г.М. Мехеда Л.В. Рибченко Л.А. Скибан Г.В. Ярошенко Н.Є. popup.nrat_date 2020-04-02 Close