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Information × Registration Number 0215U004792, 0114U000774 , R & D reports Title The role of epigenetic modification of Wnt gene regulatory pathways (GHSR, TUSC5, WIF1, DKK4 and SFRP5) in the differential diagnosis of hyperproliferative and neoplastic processes of breast and uterus. popup.stage_title Head Zaporozhan Valery Nikolaevich, Registration Date 01-12-2015 Organization Odesa National Medical University popup.description2 studied the level of methylation of genes GHSR, DKK4, SFRP5 and TUSC5 as a biomarker for the differential diagnosis of hyperproliferative diseases and cancer of the endometrium. As a result of this work proved significant difference between the content of DNA methylation of genes GHSR, TUSC5 SFRP5 and in tissue samples of endometrial cancer compared with benign tissue and the normal tissue of the endometrium. The methylation of gene promoters and WIF1 DKK4 in tissue samples of endometrial cancer compared with benign endometrial and normal endometrial tissue was not significant. Product Description popup.authors Бубнов Владимир Вячеславович Запорожан Валерий Николаевич Маричереда Валерія Генадієвна Поклад Ганна Георгіевна popup.nrat_date 2020-04-02 Close