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Information × Registration Number 0215U004834, 0112U008232 , R & D reports Title Mechanisms of changes of the mitochondria functional state and structural organization under oxidative stress of various origin. popup.stage_title Head Mankovska Iryna Mikitivna, Registration Date 09-12-2015 Organization Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine popup.description2 It was investigated development and level of oxidative stress in rat different tissues under using of neuro- and cardiotoxic agents - rotenone and anthracycline antibiotics (doxorubicin). It was established the cellular and molecular mechanisms of the mitochondrial morphofunctional changes in these tissues: the peculiarities of the morphologic and stereometric characteristics of mitochondria, the respiratory chain functioning, the mitochondrial KATP channel activity, pro- and antioxidant reactions, expression of genes and proteins, regulating the mitochondrial oxidative state. Product Description popup.authors І.М.Маньковська Бакуновський О.М. Болгова Т.В. Братусь Л.В. Гавенаускас Б.Л. Гончар О.О. Древицька Т.І. Дубова М.Г. Колєснікова Є.Е. Лінник О.О. Моісеєнко Є.В. Носар В.І. Розова К.В. Серебровська З.О. Серебровська Т.В. Стешенко М.М. popup.nrat_date 2020-04-02 Close
R & D report
Head: Mankovska Iryna Mikitivna. Mechanisms of changes of the mitochondria functional state and structural organization under oxidative stress of various origin.. (popup.stage: ). Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine. № 0215U004834
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Updated: 2026-03-24