Search academic texts

Information × Registration Number 0215U004841, 0113U000670 , R & D reports Title Study of the formation of cardiovascular lesions in patients with antiphospholipid syndrome and develop differentiated approaches to their pharmacological correction. popup.stage_title Head Shevchuk Sergiy Viktorovich, Registration Date 10-12-2015 Organization Research Institute of Invalid Rehabilitation.The M.I.Pirogov National Medical University, Vinnitsia popup.description2 Object of study: patients with antiphospholipid syndrome. Objective: based on the investigation of metabolic risk factors (hyperhomocysteinemia, dyslipidemia, inflammatory and adhesion markers, serum paraoxonase activity, thrombomodulin and endothelin levels), genetic factors of cardiovascular disease, vitamin B9 and B12 status, clarification of relations with the disease and traditional risk factors, to evaluate their pathogenetic role in the formation of cardiovascular disorders in patients with antiphospholipid syndrome and identify ways of pharmacological correction. Methods: clinical, biochemistry, ELISA, genetic, instrumental, statistic. Studied the frequency and spectrum of clinical and structural and functional manifestations of atherosclerotic lesions of the cardiovascular system in patients with antiphospholipid syndrome, examined their relationship with traditional and metabolic risk factors and characteristics of the underlying disease. Assess the impact of each of the metabolic risk factors, pathogenetic value combinations thereof, and various combinations of factors contribute to the formation of cardiovascular lesions in patients with antiphospholipid syndrome. The methods of pharmacological correction of metabolic risk factors of cardiovascular lesions in these patients. Product Description popup.authors Іваниця Надія Петрівна Безсмертна Галина Вікторівна Безсмертний Юрій Олексійович Галютіна Олена Юріївна Довгалюк Тетяна Вікторівна Заічко Наталя Валентинівна Кувікова Інна Петрівна Резнік Тетяна Андріївна Сегеда Юлія Сергіївна Станіславчук Микола Адамович Шевчук Віктор Іванович Шевчук Сергій Вікторович popup.nrat_date 2020-04-02 Close