Search academic texts

Information × Registration Number 0215U004954, 0115U000105 , R & D reports Title Investigation of possibility of creation of highly porous calcium phoshate biomaterials for bone tissue reconstruction in orthopedics and traumatology popup.stage_title Head Sych Olena Evgenivna, Кандидат технічних наук Registration Date 23-12-2015 Organization Frantzevich Insitute for Materials Science Problems of the Ukranian National Academy of Sciences popup.description2 It has been established that sintering of highly porous ceramics samples prepared by a replication of the structure of a polymer template in the temperature range 800-1100 °С using biogenic hydroxyapatite and SiO2-CaO-Na2O glass (50 wt. %) as starting materials leads to the decomposition of biogenic hydroxyapatite and interaction with the glass phase, which results in forming of renanit NaCaPO4, calcium silicate phosphate Ca5(PO4)2SiO4, calcium pyrophosphate Са2Р2О7 and impurities of hydroxyapatite Ca5(PO4)3(OH). The samples prepared at 900 °С exhibit optimal structural-mechanical properties. They are characterized by a permeatable structure with a predominant pore size of ~125 µm and a small volume shrinkage of 12 %, which makes it possible to fabricate samples with required shape, size as well as total and open porosity of 78 and 63 %, respectively, and a compressive strength of 1.0 МPа. It was found the significant increase in osteogenic activity of bone marrow stromal stem cells of human ilium outside the local foci of inflammation and degenerative lesions in the presence of highly porous ceramics samples, which makes such material promising for medical use. Product Description popup.authors Євич Ян Іванович Отиченко Оксана Миколаївна Пінчук Наталія Дмитрівна Сич Олена Євгенівна Товстоног Ганна Богданівна Томила Тамара Василівна popup.nrat_date 2020-04-02 Close