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Information × Registration Number 0215U006239, 0110U002228 , R & D reports Title "Structure-properties-functions" relationship of ligands of benzodiazepine, bradykinine, serotonine, dopamine and alpha ІІb beta 3 receptors. popup.stage_title Head Andronati S.A., Registration Date 24-03-2015 Organization A.V.Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine popup.description2 The objects of study are RGD mimetics containing 1,2,3,4-tetrahydroisoquinoline fragment, N-arylpiperazinylbutylamides of endic acid. Objective - synthesis, ascertainment of structural factors that determine the affinity of corresponding ligands for the central and peripheral benzodiazepine, serotonin 5-HT1A, dopamine D2, and alpha ІІb beta 3 receptors, determination of functional activity and pharmacological properties of these ligands. There were studied the structure, properties ligands for serotonin 5-HT1A, dopamine D2, and alpha ІІb beta 3 receptors. Specified substances possess anxiolytic and antithrombotic properties. Product Description popup.authors А.А. Крисько В.І. Павловський С.П. Смульский. Т.А. Кабанова Т.Л. Карасьова popup.nrat_date 2020-04-02 Close