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Information × Registration Number 0215U007133, 0114U001062 , R & D reports Title Rozrobiti methodological konformnoї promenevoї terapії resistant forms of cancer of the uterus shiyki popup.stage_title Head Ivankova Valentina Stepanovna, Доктор медичних наук Registration Date 13-02-2015 Organization Ukrainian Research Institute of Oncology and Radiology popup.description2 The study included 51 patient locally common forms of cervical cancer (MP cervical cancer). The objective was to improve the effectiveness of radiation treatment of patients with resistant forms of cervical cancer through the application of various methods of conformal radiation therapy (CBT) and chemoradio and radiobiological security studies. Research methods and apparatus: clinical, laboratory, cytogenetic, radominski, dosimetry. CT scanner with built-in virtual simulation - Philips (Brilliance)planning system Eclipse (Varian), a linear electron accelerator (let) "Clinac-2100 CD", GУNE SOURCE (HDR), ULTRASONIC apparatus "Aloca" - FLEXUS, apparatus for magnetic resonance imaging (MRI) "Маgnetom-Vision-Plus-System (Siemens), universal dosimeter PTW Freiburg "Unidose E". Defined stages and sequence topometric prepare patients resistant forms of cervical cancer to CPT. I study group consisted of 14 patients MP cervical cancer who had CBT for classic mode fractionation of the radiation dose on the background use chemoradio funds: on the pelvic area (tumor and its regional distribution) summed single focal dose (GENUS) 1.8 Gy to a total focal dose (SOD) 45 Gr. During the whole course of IPT patients received oral Ftorafur 800 mg per day to SJ 3,5-4,0 g and cisplatin 50 mg 1 time a week intravenous drip in SD 200-300 mg. In the second study group included 16 patients MP cervical cancer, which the CPT carried out according to the developed method fast track fractionation of the radiation dose to the pelvic area (tumor and its regional distribution) has summed up the KIND of 1.3 Gy x 2 times a day with an interval of 4 hours prior to SOD 39 Gy to the tumor and SOD 44 Gy to the lymph nodes of the pelvis. The control group consisted of 21 patients MP cervical cancer, which we carried out classical CCP : in the pelvic area were summed GENUS 1.8 Gy to SOD 45 Gr. The second stage of the course PPT patients of all groups was carried out unotron brachtherapy apparatus Gyne Source Co60 sources of high activity (HDR BT) mode GENUS 5 Gy on And so 2 times a week to SOD 35 Gy in 7 fractions. It is established that the application of the developed methods conformal RT in patients with major groups several enhances regression of tumors without increasing the toxic effects of treatment. Product Description popup.authors Іванкова Валентина Степанівна Бакай Ольга Олексіївна Барановська Лідія Михайловна Галяс Оксана Вікторівна Скоморохова Тетяна Володимирівна Хруленко Тетяна Валерівна Шевченко Галина Миколаївна popup.nrat_date 2020-04-02 Close