Search academic texts

Information × Registration Number 0215U008280, 0113U003095 , R & D reports Title Development of methods of receipt of new potentially biologically active connections by the reactions of methatesis. popup.stage_title Head Kaschkovsky V., Кандидат хімічних наук Registration Date 25-12-2015 Organization Institute of Bioorganic Chemistry and Petrochemistry of National Academy of Sciences of Ukraine popup.description2 Researches aimed at expanding opportunities of obtaining new cycloalkenyl and alkenyl-containing derivatives of pyrimidine, isooxazole, pyrazole by the ring-closing metathesis, as well as cross-metathesis reactions were performed in this year. The accessible methods of synthesis have been developed and a number of new cycloalkenyl and alkenyl-containing derivatives of these heterocycles was obtained. New cycloalkenyl containing isoxazole and pyrimidinetrione derivatives were synthesized by the ring-closing metathesis reactions of dialkenyl derivatives and a number of new functionalizing pyrazole derivatives were obtained by cross-metathesis. According to forecasts made by the program PASS, among synthesized compounds may display a biological activity with a high probability. Product Description popup.authors В.О. Євдокименко В.П. Кисельов Д.С. Каменських Т.В. Ткаченко Ю.В. Безуглий Ю.В. Кисельов popup.nrat_date 2020-04-02 Close