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Information × Registration Number 0215U009024, 0109U003990 , R & D reports Title Synthesis, physico-chemical and biological properties of derivatives of 1,2,4-triazole popup.stage_title Head Panasenko Alexander Ivanovich, Registration Date 12-08-2015 Organization Zaporozhye State Medical University. Department of psychiatry popup.description2 Laboratory methodologies of synthesis of adamanthane - are worked out, 2-methoxyphenyl-, furyl-, methylfuryl derivatives 1,2,4-triazole-3-thiol. Are the reactions of corresponding derivatives studied with halogenalkanes, ?-halogenoacids, by their esteras and ?-halogenketones and the got corresponding connections. The optimal terms of synthesis of receipt of proof salts of 1,2,4-triazole-3-thioacetic acids are offered with inorganic and organic bases; to learn co-operation 2 - (5 - R- of 1,2,4-triazole-3-ylthio) -1-arylethanones with the concentrated sulfate, by polyphosphate acids, and also with acilic agents. Intercommunication is set "structure-action" in bioactive connections of katione-anione action to get the hydrazides of amino- and thioderivatives adamanthane- and 2-methoxyphenyl derivatives of 1,2,4-triazole-3-ylthioacetatic acids. Learned co-operation of halogenderivatives adamanthane- and 2-methoxyphenyl derivatives of 1,2,4-triazole-3-ylthioacetatic acids from hydrazone Product Description popup.authors Гоцуля Андрій Сергійович Книш Євген Григорович Сафонов Андрій Андрійович Щербина Роман Олександрович popup.nrat_date 2020-04-02 Close