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Information × Registration Number 0216U000208, 0113U000116 , R & D reports Title To improve the diagnosis and surgical methods of treatment of patients with malignant neoplasms of the larynx and hypopharynx part of the pharynx popup.stage_title Head Lukach Ervin Vencelovich, Доктор медичних наук Registration Date 25-01-2016 Organization Kiyv Research Institute of Otolaryngology named after prof. O.S.Kolomiychenko popup.description2 The study of the efficiency of diagnosis and surgical treatment of patients with malignant tumors of the larynx and hypopharynx. Morphological study showed that the area of tissue with weak positive autolyuminestsentsiey significantly more consistent simple hyperplasia stratified squamous epithelium, and otsuotstvie endoscopic tissue autolyuminestsentsii corresponds squamous cancer. Using autoflyuorestsentsiiї at fibrovideoendoskopii improves performance sensitivity and accuracy of diagnosis of cancer of the larynx and hypopharynx its low specificity. Sensitivity, specificity, and accuracy of the method was 92.2%, 20% i79,1% respectively. It was found that the use of hepatic arginisoderzhaschih in combination of sorbents at visokodoznoy chemotherapy significantly reduces the symptoms of gastrointestinal toxicity (p <0,05), improves overall and disease-free one-year vizhivaemost patients. Developed and improved methods of reconstruction of the larynx and hypopharynx, after removal of the tumor by using autografts. Improved plastic tracheostomy, which prevents contraction and deformation of the stoma. It was found that a significant factor in 74.5% of cases, the spontaneous formation of defects orofaringoezofagealnyh have application in cancer chemotherapy patients with a full course of radiation therapy and combined therapy. Product Description popup.authors Діхтярук В.Я. Зайцева-Гринь Н.В. Клочков Є.І. Сережко Ю.О. Стрежак В.В. Цимбалюк Є.М. popup.nrat_date 2020-04-02 Close