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Information × Registration Number 0216U001463, 0115U000809 , R & D reports Title To develop a complex cytological diagnostics of pancreatic and liver tumors with the use of modern cytological studies popup.stage_title Head Bolgova lydiya Sevstiyanovna, Доктор медичних наук Registration Date 16-02-2016 Organization Ukrainian Research Institute of Oncology and Radiology popup.description2 Object of research: cytological preparations of pancreatic neoplasms. Aim - To develop and improve a complex cytological diagnostics of pancreatic and liver tumors with the use of modern cytological studies. Methods: cytological, cytogenetic, statistical. Facilities: microscopes OLYMPUS - СX 21, СХ 41. As a result of a complex study of needle biopsy materials from pancreatic neoplasms there have been revealed cytomorphological and cytogenetic patterns of these tumors which improve the determination of histological types of pancreatic tumors, their proliferation activity, and biologic potency; such approach will increase an efficacy of cytological diagnostics, and will be useful in clinical practice as a way to find an optimal choice for patient's therapy. The determination of quantitative and qualitative cytoplasmic, nuclear, nucleolar features of malignant pancreatic tumor cells and their background parameters in cytological preparations augments the already known data, allows to ascertain the presence of malignant patterns and to justify a histological type of a neoplasm, and improves an efficacy of cytological diagnostics. The performed cytogenetic studies allowed to determine at subcellular level the degree of ribonucleoprotein exchange using the study of high active and low active morphofunctional nucleolar types, what is useful for determination of a character of pathologic process. The results of the studies have been reported on a congress, conferences, seminars, and were published in specialized journals; these results are recommended for the use in cytological diagnostics at different stages of examination of patients with pancreatic neoplasms for more precise determination of a character of pathologic process and better treatment results and prognosis. Product Description popup.authors Болгова Лідія Севастянівна Мариненко Світлана Вячеславівна Махортова Марина Геннадіївна Туганова Тамара Миколаївна popup.nrat_date 2020-04-02 Close