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Information × Registration Number 0216U001751, 0113U001519 , R & D reports Title Research on the role of distal intestinal tract microflora in maintaining oxalate homeostasis popup.stage_title Head Osolodchenko Tatiana Pavlivna, Registration Date 04-04-2016 Organization The Mechnikov Research Institute of microbiology and immunology at Kharciv popup.description2 The object of research: fecal bacterial microflora of patients with disorders of oxalate homeostasis and persons from control group; clinical strains of Lactobacillus spp. and E. coli; strains of Lactobacillus spp. from commercial probiotic preparation. Objective: to establish the relations between the composition of microflora in distal intestinum and the state of oxalate homeostasis in patients with oxaluria and urolithiasis. Research Methods: microbiological, statistical. Qualitative and quantitative composition of distal intestinal tract microbiocenosis was characterized in patients with disorders of oxalate homeostasis and in persons of control group. Nutrient medium for the detection of oxalate degrading bacteria was developed and used for selection of several perspective strains of Lactobacillus spp. and E. coli, applicable in probiotic preparations for oxalate homeostasis correction through influence on intestinal microbiota oxalate degrading activity. Strains were characterized by their biological characteristics and sensitivity to antibiotics. Product Description popup.authors Волянський Д. Л. Осолодченко Т. П. Пономаренко С. В. Порт О. В. Суржко Е. Штикер Л. Г. popup.nrat_date 2020-04-02 Close