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Information × Registration Number 0216U002093, 0115U004836 , R & D reports Title ASIC channel blockers for the treatment of brain traumas popup.stage_title Head Maximyuk Oleksandr Petrovych, Registration Date 25-01-2016 Organization Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine popup.description2 It held directed synthesis of new chemical compounds in an amount of 36 units. Patch-Clamp method investigated the activity of the synthesized compounds on isolated cells of rat hippocampus. Determined the cytotoxicity of the active compounds on organotypic hippocampal slice cultures using modern techniques. Selected promising compounds (most active and less cytotoxic) - as potential neuroprotective agents. Recommendations for further preclinical studies of the compounds obtained. Product Description popup.authors Єгорова Олена Володимирівна Ісаєв Дмитро Сергійович Волкова Тетяна Михайлівна Кришталь Олег Олександрович Максимюк Олександр Петрович Хмиз Володимир Васильович popup.nrat_date 2020-04-02 Close