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Information × Registration Number 0216U003555, 0115U002701 , R & D reports Title Justification methods of correction of endothelial dysfunction and emotional state disorders in children, residents of radioactively contaminated areas, and children who are displaced from the southeast Ukraine popup.stage_title Head Stepanova Yevgeniya Ivanovna., Доктор медичних наук Registration Date 01-02-2016 Organization State institution "National research centеr for radiation medicine of the National academy of medical sciences of Ukraine " popup.description2 Object of study: children - residents of contaminated areas and children moved from areas where the zone of antiterrorist operation. Objective: To determine the tools that can positively affect different pathogenesis of endothelial dysfunction and to assess the effectiveness of normobaric hipoksyhenatsiyi and ARV therapy for correction of endothelial dysfunction and disorders of mental and emotional state of the children, residents of radioactively contaminated areas and children displaced from the southeast Ukraine . Research Methods: clinical, laboratory, instrumental, statistics. Results and novelty. Children who in addition to receiving basic therapy sessions intermittent normobaric, there is a more pronounced positive therapeutic effect, good tolerability, no side effects. There was increasing performance bronchial obstruction proximal and distal bronchi, eliminate hidden bronchospasm. Determined the positive changes in the functional state of the endothelium in 54.5% of children. Study of nitric oxide showed increased content in serum L-arginine in the absence of significant changes in levels of stable NO metabolites in children with endothelial dysfunction. The decrease of lipid peroxidation - a reduction of serum lipid peroxidation end products that react with tiobarbiturovoyu acid. Established that the use of children in residents of contaminated areas endothelial dysfunction intermittent normobaric is a tendency to reduce the severity of cardiovascular syndrome maladjustment and improved adaptive responses at both central regulatory units and peripheral receptors. Marked probable increase in aerobic capacity of the organism index Robinson, but he has not reached the level of children in the control group and healthy. There are a number of significant trends, namely, normalization of sinus rhythm; reducing the frequency of violations according to ECG repolarization; reducing imbalances various circuits control heart rhythm. Detected immunomodulatory effect: increasing the functional activity of neutrophils, normalization of humoral immunity, reducing the concentration of fine and velykodyspersnyh circulating immune complexes. The use of art therapy has a positive effect on children's health by reducing the adverse clinical manifestations of psychological states and optimizing adaptive capabilities child's body. It was established that the use of art therapy has a positive impact on the psycho-emotional condition and optimizes adaptation and adaptive capabilities child's body, reduces states: anxiety, nervous and mental exhaustion and aggression Product Description popup.authors Вікторія Анатоліївна Позниш Вдовенко Віталій Юрійович Гриценко Тетяна Володимирівна Зігало Віктор Миколайович Колпаков Ігор Евгенович Кондрашова Валентина Григорівна Лісуха Любов Михайлівна Леонович Олена Семенівна Литвинець Оксана Михалівна Скварська Олена Олександрівна popup.nrat_date 2020-04-02 Close