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Information × Registration Number 0216U003667, 0111U000153 , R & D reports Title Cytological mechanisms of gravitational-dependent changes in a skeleton and hemohenesis bodies at the land vertebrates popup.stage_title Head Rodionova Natalia Vasilievna, Registration Date 03-02-2016 Organization Schmalhausen Institute of Zoology popup.description2 Object of research - samples of bodies and the tissues, that were received at representatives of the 4th classes land vertebrates. The work purpose - definition of cellular mechanisms of adaptation of a bone skeleton and the hemohenesis bodies to decrease the mechanical loadings at the land vertebrates. Methods: histological, histochemical, cytochemistry, transmission and raster electron microscopy, autoradiography using radionuclides 3H-thymidine and 45Ca, morphometric and statistical analysis, programs for processing of light microscopes images. On representatives of classes (Amphibia, Reptilia, Aves, Mammalia) who differ as musculoskeletal loadings and in model experiments on mammals with removal of basic loading of extremities, in the experiments on biosatellite "Bion-M1" new data for science about morpho- functional features of cartilaginous height zones formation and the bone formation centres, the structure of a vascular bed and its cell-like structure in extremities' areas of bone remodeling; ultastructure and specific functioning of bone tissue cells (osteoblasts, osteocytes); about dynamics of updating of cell populations and some mechanisms of adaptive remodelling of bone structures; cellular structure, ultrastructural features and histogenetic potential of bone marrow stromal cells of the amphibians and reptiles representatives conditions were obtained. Differences in intensity of a hemopoiesis in different departments of hemopoietic system at representatives of poikilothermal animals depending on locomotion types were established. Results of the study bring new to the understanding of cellular mechanisms of gravitational-dependent changes in skeleton bone tissue and the hemopoietic bodies at land vertebrata. Results of NDR have fundamental value, and also can be used in biotechnology and medicine when developing methods of treatment and prophylaxis of osteoporosis and bone reparation. Are recommended also for inclusion in training programs and textbooks on a cytology, a histology, а zoology. Keywords: bone tissue, cartilaginous tissue, cells, hypokinesia, weightlessness, land vertebrates, histology, electron microscopy, radioautography. Product Description popup.authors Акуленко Наталія Михайлівна Дзюбенко Наталія Вікторівна Житніков Анатолій Якович Золотова -Гайдамака Надія Вікторівна Катькова Олена Володимирівна Нестеренко Ольга Миколаївна Родіонова Наталія Василівна Сивальнев Валентин Митрофанович Скрипченко Олена Володимирівна Шевель Іван Михайлович popup.nrat_date 2020-04-02 Close