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Information × Registration Number 0216U003692, 0114U003079 , R & D reports Title Development environment and technologies of the regulated biosynthesis of selenium-metal biologically active substances unicellular algae popup.stage_title Head Vasyl Grubinko, Доктор біологічних наук Registration Date 04-02-2016 Organization Volodymyr Gnatyuk Ternopil State Pedagogical University popup.description2 By methods of biochemical analysis, atomic-absorption spectrophotometry, dividing and gas-liquid chromatography, ultracentrifugation, including of radio-active mark is first set a mechanism of it were obtained and allocated stable selen-lipid and selen-zinc-lipid substances in a result of incubation of unicellular algae Chlorella vulgaris Beij. in aquaculture with sodium selenite and zinc sulfate.Their influence on oxidative and energetic status of healthy rat was investigated. It were suppressed prooxidative processes, activated antioxidant status, succinate dehydrogenase and cytochrome oxidase activity and glutamate dehydrogenase way of formation of glutamate were increased when substance at a dose of 0.4 mcg of selenium, 2.5 mcg of zinc and 0.5 mg of lipid per 1 ml of 1% starch-water suspensions was introduced in organisme of healthy rats. Also it contributed of formation and functioning of the active components of the antioxidant system - catalase, ceruloplasmin, reduction glutathione in a liver and in a blood serum of experimental animals.. It is inculcated in Institute of hydrobiology of NAS of Ukraine. It is recommended for introduction to Ministry of ecology and natural environment of Ukraine, Ministry of agrarian political of Ukraine. Product Description popup.authors Боднар О. І. Вінярська Г. Б. Василенко О. В. Войтюк В. Б. Грубінко В.В Грубінко У. П. Луців А. І. Станіславчук А. В. popup.nrat_date 2020-04-02 Close