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Information × Registration Number 0216U005286, 0115U002696 , R & D reports Title The investigation possibility of modification the radiation-induced mutagenesis in human peripheral blood lymphocytes in vitro using astaxanthin popup.stage_title Head Pilinska Maria Andriivna, Доктор медичних наук Registration Date 21-01-2016 Organization State institution "National research centеr for radiation medicine of the National academy of medical sciences of Ukraine " popup.description2 Object of study - non-irradiated lymphocites - intact and exposed in vitro by astaxanthin in several concentrations.The aim of study - to establish baseline frequencies of cytogenetic and epigenetic parameters in non-irradiated blood lymphocytes;determination of astaxanthin optimal working concentration in vitro, suitable for further cytogenetic and molecular-genetic studies. Shown that the frequencies of aberrant cells in non-irradiated peripheral blood lymphocytes mathed to age population-based data. Optimal working concentration of astaxanthin (20 mkg/ml) detmined for further evaluation of its capabilities to modify radioinduced effectsby cytogenetic and epigenetic criteria. Field of application - radiation genetics, radiobiology, radiation medicine. Product Description popup.authors Єремєєва М.Н. Дибська О.Б. Курінний Д.А. Степанова Л.С. popup.nrat_date 2020-04-02 Close