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Information × Registration Number 0216U005550, 0113U000876 , R & D reports Title Structural and functional state of hemoglobin under the alcoholic intoxication and physiologically active substances popup.stage_title Head Sybirna Nataliya Oleksandrivna, Dudok Katerina Petrivn, Registration Date 03-02-2016 Organization Ivan Franko National University of Lviv popup.description2 The effect of different concentrations of acetaldehyde in causing oxidative stress for alcohol intoxication, enhanced understanding of the cellular and molecular mechanisms of manifestation of complications for alcohol intoxication; use of L-arginine and L-NAME in therapeutic and prophylactic purposes under alcohol intoxication. It was shown changes in the activity of antioxidant enzymes (superoxidedismutase, catalase) and NO-synthase (NOS), in the content of stable metabolic products of nitric oxide and levels of secondary lipid peroxidation products in erythrocytes of rats under alcoholic intoxication. It was normalization of parameters of prooxidant-antioxidant under the admission of the main substrate, NOS - L-arginine to animals per os. The results testify that L-arginine has antioxidant properties, whereas L-NAME exerts a slightly stabilizing influence. Product Description popup.authors Єфіменко Наталія Валентинівна Федорович Андрій Миколайович popup.nrat_date 2020-04-02 Close