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Information × Registration Number 0216U006091, 0113U002701 , R & D reports Title Investigation of bone mineral density in patients with diabetes popup.stage_title Head Kirilyuk Mikhail Lasarevich, Registration Date 26-01-2016 Organization Ukrainian scientifical-practical centre of endocrine surgery, endocrine organs and tissues transplantation of Ukrainian Ministry of Health popup.description2 Purpose: The study of bone mineral density in post menopausal women with type 2 diabetes while considering factors such as duration of disease, level of compensation of carbohydrate metabolism and the type of anti diabetic medication used; evaluation of the role of polymorphism of genes which encode the metabolic and osteoporotic processes of the bone (COL1A and VDR), analysis of medico- psychological aspects of pathogenesis of psycho-endocrine syndrome in diabetes. The problem of osteoporosis is becoming increasingly important. It is connected with the widespread enlargement of life expectancy. Increasing the number of older people is accompanied by rise frequency of metabolic diseases, including osteoporosis first of all. The presence of type 2 diabetes and menopause significantly worsens the prognosis of patients. The research was devoted to define of communications of single nucleotide polymorphisms (SNP) COL1A1 gene rs1800012, 1107946 and VDR gene rs731236, rs11568820 on the development of postmenopausal osteoporosis risk, calcium and phosphorus levels, levels of osteoassociated hormones and biologically active agents. Product Description popup.authors В.В. Іщук Д.С. Зябліцев Л.В. Щекатурова М.Л. Кирилюк О.Е. Третяк popup.nrat_date 2020-04-02 Close