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Information × Registration Number 0216U006749, 0110U007827 , R & D reports Title Modern aspects of clinic-liquorological diagnostics in neurology, neurosurgery, psychiatry popup.stage_title Head Potapov Olexandr, Registration Date 17-05-2016 Organization Sumy State University popup.description2 Object - the acute phase of ischemic stroke. Purpose - to explore the features of functional changes in cerebral vascular endothelium and blood-brain barrier in patients in the acute period of ischemic stroke to develop diagnostic criteria for severity of illness and treatment optimization. Methods - general clinical, biochemical laboratory, instrumental and mathematical-statistical. The study found the relationship between the main indicator of permeability of the blood-brain barrier - albumin, severity of patients, CSF-hypertensive syndrome capacity of the affected zone, indicating pathogenic role in the development of ischemic stroke. Identified significant correlation relationships between indicators of BBB permeability main factors - NO and endothelin-3, severity and volume of patients affected area of the brain. The results of research are introduced in the educational process of the department of Neurosurgery and Neurology of Medical Institute of SSU in practice SRCH, SCCH №4, KCCH №7, ZCCH №6. Projected assumptions about the object of research - the search for more specific treatment approaches in acute period of ischemic stroke identified the light changes. Product Description popup.authors Кмита О.П. Коленко О.І. Кустов А.В. Личко В.С. Мудренко І.Г. Сотніков Д.Д. Юрченко А.В. popup.nrat_date 2020-04-02 Close