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Information × Registration Number 0216U007093, 0113U001657 , R & D reports Title The role of anti-tumor mechanisms in the therapeutic effect and effectiveness of complex immunotherapy at eye-preserved methods of treatment in patients with tumors of the eye, eyelids and orbits popup.stage_title Head Vit Valeriy V., Доктор медичних наук Registration Date 05-04-2016 Organization The Filatov Research Institute of Diseases and Tissue Therapy popup.description2 Radioсryosurgical (RC) treatment of malignant epithelial tumors (MET) of eyelid skin allows to extend the indications for treatment and avoid crippling operations in 44.7% - 54.2%, to obtain good functional and aesthetic result, improving the quality of life of patients. Established risk factors for recurrence of MET: availability index Всl-2/СD95>1,0 (the risk of recurrence rises to 21.5 times). Of the total scoring assessment of relative values of expression of p53, vcl-2, CD95 and IPO38 amount in> 76.2% with a sensitivity of 97.1% and a specificity of 85.0% predicted tumor recurrence. The biological aggressiveness of tumors associated with high proliferative activity (overexpression of p53 and ICE-38), a decrease of apoptosis by hipoexpression of bsl-2 and the lack inducer of apoptosis CD95. Lasercoagulation of iris tumors using ? = 0,53 m and ? = 0,57 leads to tumor resorption with laser power ranging from 80 to 450 mW, spot diameter 50-200 mm, exposure 0.1-0.15 sec depending on pigmentation and localization. Lasercoagulation with ? = 0,57 microns is effective in patients with vascular tumors. There was studied the manifestations and increasing of extraocular muscles at different stages and forms of endocrine ophthalmopathy Product Description popup.authors Єлагіна Вікторія Анатоліївна Богданова Олександра Вікторівна Буйко Олександр Сергійович Віт Валерій.Вікторович Величко Людмила Миколаївна Гузун Ольга Володимирівна Малецкий Анатолій Парфентіович Молчанюк Наталія Івангівна Полякова Світлана Іванівна Репях Володимир Семенович Сафроненкова Ірина Олексіївна Цуканова Інна Веніамінівна Чечин Петро Павлович popup.nrat_date 2020-04-02 Close