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Information × Registration Number 0216U007099, 0113U001663 , R & D reports Title The influence of polymicroelementary of sea concentrate on the metabolic and regenerative processes in the cornea in modeling traumatic keratitis popup.stage_title Head Sotnikova Elena P., Доктор медичних наук Registration Date 05-04-2016 Organization The Filatov Research Institute of Diseases and Tissue Therapy popup.description2 Results and Novelty. In the laboratory, prototypes prepared the solution of a standard 1% polimikroelementary concentrate of the sea water. Synonym: the preparation of sea water (PSW). Courses instillation PSW do not cause irritant actions, have not allergenic effect, don't violate the integrity of the corneal epithelium, do not affect the tearproduction, do not change the state of the fundus, the hemodynamics of eyes, do not violate the histological structure and ultrastructure of the cornea. 7-day instillation PSW cause a significant increase in the amplitude of the response to light and reduction of WGD. 14-day course PSW does not affect the activity of the enzymes LDH, SCHF, KF, catalase, MDA in lacrimal fluid (LF) and serum (S) of the healthy rabbits. Noticed the tendency to increase the activity of the enzyme lysozyme and ceruloplasmin. In the context of traumatic keratitis instillation PSW antiinflammatory and regenerative effect, helps with autosterilization of eyes (no growth of pathogenic microflora) compared to the control. Medical instillation PSW increase nonspecific resistance of significantly increasing the intensity of the process of phagocytosis (phagocytic activity, the index number); It does not affect the activity of the enzyme lactate dehydrogenase, alkaline phosphatase, SJ and CF in the LF and S; retain antioxidant protection (catalase enzyme activity,the CP and MDA) compared to control; normalize the activity of the enzyme lysozyme as a non-specific factors of local immunity. Product Description popup.authors Іванов Валерій Іванович Абрамова Ганна Борисівна Болотич Лідія Дем'янівна Лотош Тамара Дмитрівна Молода Алла Леонідівна Осташевський Віктор Леонардович Салдан Вікторія Йосипівна Сотнікова Олена Петрівна Фесюнова Галина Степанівна Цибуляк Ганна Михайлівна Шеріна Наталія Муртузалієвна popup.nrat_date 2020-04-02 Close