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Information × Registration Number 0216U008181, 0115U005102 , R & D reports Title Highly porous glass ceramics materials with structure close to that of cancellous bone tissue for reconstructive surgery popup.stage_title Head Sych Olena Evgenivna, Кандидат технічних наук Registration Date 14-12-2016 Organization I.N.Frantsevich Institute for Problems of Materials Science of NAS of Ukraine popup.description2 According to the investigation of structure and properties of highly-porous glass-ceramics prepared based on biogenic hydroxyapatite (50, 60, 66,7 and 70 wt. %) and glass of the SiO2-Na2O-CaO system it was established that prepared samples have permeable open porous structure with the total porosity 78-85 % that increase with increasing of biogenic hydroxyapatite amount in the initial composition.Furthermore, decrease the amount of biogenic hydroxyapatite in the initial composition and, accordingly, increase the amount of glass f leads to consolidation of pores, and narrowing of the distribution region of dominant amount of pores in the glass-ceramic structure. It was shown that highly-porous glass-ceramics samples contains in the initial composition 50-60 wt. % of biogenic hydroxyapatite satisfy the structural and mechanical requirements for highly porous implant materials. It was established that prepared bioactive materials are resorbable and promote activation of proliferation and osteogenic differentiation of precursor cells of the bone marrow that experimentally proves the possibility and feasibility of clinical application of such material to replace bone defects of different origin in orthopedics and traumatology. Product Description popup.authors Сич Олена Євгенівна Товстоног Ганна Богданівна popup.nrat_date 2020-04-02 Close