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Information × Registration Number 0216U008318, 0115U005687 , R & D reports Title Role of MRPS18-2 protein in regulation of cell cycle and cancerogenesis popup.stage_title Head Kashuba Olena Vitaliivna, Доктор біологічних наук Registration Date 27-12-2016 Organization R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology popup.description2 During the project found another protein that interacts with the S18-2, - RNF2. Protein has properties RNF2 E3 ubiquitin ligase for histone 2A (H2A). We have shown that in the case of simultaneous expressioni S18-2 and RB protein in fibroblasts RB1 knockout mice formed a multi-protein complexes that contain RB, S18-2, prohibitin, RING1, and RNF2. As a result, induced mono ubikvitination H2A, which is characteristic of stem cells. Product Description popup.authors Бреєва Ольга Володимирівна Бучинська Любов Георгіївна Кашуба Олена Віталіївна Ковалевська Лариса Миколаївна Чехун Василь Федорович Юрченко Наталя Петрівна popup.nrat_date 2020-04-02 Close