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Information × Registration Number 0216U008333, 0116U002095 , R & D reports Title Development the accompanying detoxication for patients with leukemia during realization of intensive cytostatic therapy. popup.stage_title Head Starikov A.V., Registration Date 29-12-2016 Organization Kiev Research Institute of Haematolojy and Blood Transfusion popup.description2 It was investigated 19 acute leukemia patients that were treated by 34 courses of high dose chemotherapy Methods: Clinical, biochemical. It was established that toxic effects of chemotherapy appear on the third day at the beginning of the high dose chemotherapy course, reache a maximum on 9th day and slightly reduce under the influence of detoxification therapy on the 14th day. The most mucous gastrointestinal tract's lesions were observed in patients, treated by high doses methotrexate. The most severe toxic effects revealed in patients who were administrated high-dose methotrexate and cytarabine. Medical and social effect. Medicine. Product Description popup.authors Баронська Лілія Валеріївна Кисельова Олена Анатоліївна popup.nrat_date 2020-04-02 Close