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Information × Registration Number 0216U010223, 0116U007061 , R & D reports Title Ribosome as a regulatory element of metabolism: new understanding on the basis of genomic engineering approaches popup.stage_title Head Ostash Bohdan Omelianovych, Доктор біологічних наук Registration Date 23-12-2016 Organization Ivan Franko National University of Lviv popup.description2 Subject - regulatory processes at the level of translation that lead to qualitative and quantitative changes in cell biology. Object gene rpsL of Streptomyces albus J1047 encoding ribosomal protein S12. Goal - to compare properties of Streptomyces albus and its rpsL-mutants, particlarly their capacity to grow, produce and resist antibiotics. Secondary metabolism of these strains has been investigated. Peculiarities of growth of the strains and antibiotic resistance were studied. A number of new improved (with respect to secondary metabolism) strains was generated via introduction of multiple spontaneous antibiotic resistance mutations. Product Description popup.authors Білик Богдан Романович Громико Олександр Миколайович Дацюк Юрій Ростиславович Осташ Ірина Степанівна Федоренко Віктор Олександрович popup.nrat_date 2020-04-02 Close