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Information × Registration Number 0217U000012, 0116U000187 , R & D reports Title To study the local immunomorphological reactions of lung tissue in patients with chronic tuberculous process popup.stage_title Head Liskina Irina Valentinovna, Доктор медичних наук Registration Date 05-01-2017 Organization SO "National institute of phthisiology and pulmonology named after F. G. Yanovsky NAMS of Ukraine" popup.description2 Object - 170 histological samples of lung tissue with tuberculomas. Methods - immunohistochemical, histologic, statistical. Aim - to determine immunomorphological manifestations of local cells reactions that are characteristic of specific chronic tuberculous inflammation in human lung tissue. It was found that peculiarities of immunocompetent cells in activ specific inflammatory process in lung tissue with tuberculoma are next : a significant increasing ща the number of CD3+ cells in follicle-like aggregates and granulomas, CD20+ cells in the fibrous layer of the capsule tuberculoma and granulomas, CD4+ cells - in the granulation layer of tuberculoma, CD8+ cells - in capsule of tuberculoma, significant decrease CD4+ cell in granulomas and the value of the immunoregulatory index in the normal range. Sphere of application - phthisiology, pathomorphology Product Description popup.authors Загаба Людмила Михайлівна Кузовкова Світлана Дмитрівна Ліскіна Ірина Валентинівна Мельник Ольга Олександрівна Рекалова Олена Михайлівна popup.nrat_date 2020-04-02 Close