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Information × Registration Number 0217U000231, 0116U007382 , R & D reports Title The study of "structure-effect" correlations and purposeful synthesis of new substances possessing antibacterial and antituberculosis activity based on 4-thiazolidinone and 1,2,4-triazole-3-thione scaffolds. popup.stage_title Head Devinyak Oleg Teodoziyovych, Registration Date 24-01-2017 Organization State Higher Educational Institution "Uzhgorod National University" popup.description2 The two new prognostic model "structure-activity" satisfactory statisticalperformance have been developed. These models can be used to forecast the activity of new yet not synthesized substances and to carry out virtual screening. Interpretation of received models revealed unknown structural features that contribute to the manifestation of antimicrobial and anti- tubercular activity. The synthesis of 22 designed new representatives of thiazolidinone and 1,2,4-triazole-3-thione classes has been performed. The moderate antimicrobial activity has been found for several compounds regarding S. Aureus (compound 9) and E. coli (compounds 2, 3, 13). Besides that, tellurium-containing salts of compound 20 were found to have weak anti-tubercular properties Product Description popup.authors Девіняк Олег Теодозійович Панто Валерій Валерійович Фізер Максим Михайлович popup.nrat_date 2020-04-02 Close
R & D report
The study of "structure-effect" correlations and purposeful synthesis of new substances possessing antibacterial and antituberculosis activity based on 4-thiazolidinone and 1,2,4-triazole-3-thione scaffolds.
Head: Devinyak Oleg Teodoziyovych. The study of "structure-effect" correlations and purposeful synthesis of new substances possessing antibacterial and antituberculosis activity based on 4-thiazolidinone and 1,2,4-triazole-3-thione scaffolds.. (popup.stage: ). State Higher Educational Institution "Uzhgorod National University". № 0217U000231
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Updated: 2026-03-25


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