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Information × Registration Number 0217U000276, 0116U002815 , R & D reports Title ASIC channel antagonists in the treatment of traumatic brain injury popup.stage_title Head Maximyuk Oleksandr Petrovych, Registration Date 25-01-2017 Organization Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine popup.description2 It held directed synthesis of new chemical compounds in an amount of 40 units. Patch Clamp method investigated the activity of the synthesized compounds on isolated cells of rat hippocampus. Determined the cytotoxicity of the active compounds on organotypic hippocampal slice culture. Selected promising compounds (most active and less cytotoxic) - as potential neuroprotective agents. Recommendations for further preclinical and clinical studies of the compounds was obtained. Product Description popup.authors Єгорова Олена Володимирівна Ісаєв Дмитро Сергійович Волкова Тетяна Михайлівна Кришталь Олег Олександрович Максимюк Олександр Петрович popup.nrat_date 2020-04-02 Close