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Information × Registration Number 0217U000803, 0114U000514 , R & D reports Title Experimental investigation of the regenerative potential of intact and induced bone marrow stromal cells and adipose tissue, and their use in the creating of tissueingeneric constructs and as a model for studying the molecular mechanisms and future therapies for some genetic diseases. popup.stage_title Head Khvysuk A.N., Registration Date 02-03-2017 Organization Kharkiv Post-Graduate Medical Institute popup.description2 Object of study - the stroma cells of the bone marrow and adipose tissue. Purpose - to study the regenerative potential of bone marrow stromal cells and adipose tissue, development of technology use tkaneinzhenernyh designs for the treatment of various origins. The study of the molecular mechanisms of some genetic diseases (including laminopatiy). Research methods - histological, cultural, cytological, clinical, statistical. A: Research on Migration MSC-labeled bone marrow and skin fibroblasts after systemic and local transplantation in rats after burn wound model; study osteogenic properties of bone marrow cells and fat rabbit; Lamin nuclear research role in osteogenic differentiation of mesenchymal stem cells. The methods of transplantation of bone marrow stem cells as part of tkaneinzhenernyh designs on kolapanoviy fibrin matrix and media. Established: concurrent systemic administration of MSCs cultures CM and FB skin may be effective in healing the wounds of post; administration of autologous SKKM on a matrix of fibrin Collapan or enhances recovery processes to regenerate the area; Lamin gene mutations affect the effectiveness of osteogenic differentiation MMSK. CELL stromal bone marrow and adipose tissue ischemia, biodegradable substrates, burns, Lamin. Product Description popup.authors Григор'єва Т.Г. Забірник А.С. Кульшин В.Є. Маркелова О.В. Омельченко О.А. Панібратцева С.Г. popup.nrat_date 2020-04-02 Close