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Information × Registration Number 0217U001007, 0115U001403 , R & D reports Title Establishment and characterization of cell based co-culture model of tumor and stromal cells for anticancer agents effectiveness evaluation popup.stage_title Head Filonenko Valeriy Viktorovitch, Доктор біологічних наук Registration Date 05-01-2017 Organization Institute of Molecular Biology and Genetics of NASU popup.description2 During the work the model for studies of migration of tumor cells based on three-dimensinal cultures and socultivation with stromal cells was optimized and characterized. It was established that morphologycal structure of lamelopodia as well as the character of migration of tumor cells from multicellular spheroids on the growth surface and monolayer of fibroblasts were significantly different. It was established that during migration of carcinoma cells from multicellular spheroids on growth surface and fibroblast monolayer S6K1 translocates from cytoplasm to the nucleus. Product Description popup.authors Філоненко Валерій Вікторович Хоруженко Антоніна Іванівна popup.nrat_date 2020-04-02 Close