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Information × Registration Number 0217U001346, 0112U002192 , R & D reports Title Morpho-functional, immunophenotypical and molecular-genetic characterization of lymphoid cell populations in lymphoproliferative processes and solid neoplasms popup.stage_title Head Gluzman Danylo Fishelevych, Доктор медичних наук Registration Date 07-02-2017 Organization R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology popup.description2 The complex study of B-CLL patients based on cytomorphology, cytochemistry, immunophenotyping and molecular biology techniques allows for delineating the features useful for the differential diagnosis between B-CLL, hairy cell leukemia, splenic non-Hodgkin lymphoma, and prolymphocytic leukemia. Aminolevulinic acid-mediated photodynamic responsiveness of lymphoid cells in B-CLL is inversely correlated with the content of smudge cells in the blood smears. Apoptosis-associated genes BCL-2, BAX, MYC, FAS-1, P38MAPK, and P53 in malignant lymphoid cells were upregulated. The impairment of DNA mismatch-repair system in cells of endometrial carcinoma in patients with the family history of cancer is associated with the decreased activity of the repair systems in peripheral blood lymphocytes of these patients. Product Description popup.authors Іванівська Тетьяна Степанівна Бучинська Любов Георгіївна Гамалія Микола Федорович Глузман Данило Фішелевич Завелевич Михайло Петрович Кашуба Олена Віталіївна Коваль Стелла Володимирівна Несіна Ірина Петрівна Скляренко Лілія Михайлівна Фільченков Олексій Олексійович Шишко Євгенія Денисівна Штонь Ірина Олександрівна popup.nrat_date 2020-04-02 Close