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Information × Registration Number 0217U002017, 0113U006629 , R & D reports Title Development of new areas of anesthesia and perioperative support in various fields of surgery and intensive care options for critical and terminal states, the development of new technology substitution therapy and renewal of life support systems popup.stage_title Head Kobeliatsky Yury Yurievich, Registration Date 05-01-2017 Organization Dniepropetrovsk State Medical Academy popup.description2 The object of study: in the experiment - 720 of nonlinear rats, in the clinic - 821 patients. Objective: Development and optimization of methods of intensive care at various critical conditions, intra- and postoperative analgesia techniques with regard to their cognitivesaving orientation. Methods: clinical, morphological, tissue metabolism, redox processes, indicators of the inflammatory response, biochemical markers of apoptosis. Results: improved treatment results, increased the speed of self-discharge of gases from 3,2±0,8 to 2,2±0,6 days, self-defecation - from 4,1±0,8 to 2,8±0,7 days and reduced the patient's stay in ICU from 4,0±0,3 to 2,8±0,3 days, reduced mortality by 26.1% and chance of die up to 8 times less frequently (OR = 8,667 [2,412; 31,141]) immediately after surgery intervention, at 6 months after surgery affect the quality of life of patients, reducing neurological deficit, which is confirmed by the absence of differences in stock likely to have minimal neurologic deficit (OR = 2,550 [0,392; 16,587]) with a decrease in postoperative mortality, and in the long term improved survival function up to 5 years of observation. Degree of implementation: Dnipropetrovsk, Vinnytsia, Zaporizhia, Kharkiv, Kyiv regions. The relationship with other works: This work continues the previous departments research "Development of new technologies of anesthetic management in various fields of surgery and intensive care techniques critical states of different origins". Scope: anesthesiology and intensive care, surgery, neurosurgery. Conclusions: The use of the methods of intensive therapy of various critical states to reduce the number of complications, mortality, patients inhospital days. The use of the proposed methods of anesthesia improves handling and safety of anesthesia. Product Description popup.authors Дудукіна Світлана Олександрівна Дьомін Сергій Володимирович Кобеляцький Юрій Юрійович Кріштафор Артур Анатолійович Мальцева Людмила Олексіївна Панченко Георгій Володимирович Петрошенок Євген Володимирович Семененко Андрій Ігоревич Тютюнник Андрій Григорович Усенко Людмила Василівна Царьов Олександр Володимирович Черненко Вікторія Григорівна Шайда Оксана Олександрівна popup.nrat_date 2020-04-02 Close