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Information × Registration Number 0217U002169, 0114U002012 , R & D reports Title To define predictors of progression and to develop measures of medical prevention of chronic secondary pyelonephritis in children popup.stage_title Head Bagdasarova I.V., Registration Date 25-01-2017 Organization Institute of Nephrology Ukraine Academi Science of Medicine popup.description2 Determined the causes of recurrence pyelonephritis for children of different age groups.It is established that in children with relapsing secondary pyelonephritis have secondary immunodeficiency with increase CD3, CD8-lymphocytes, B-lymphocytes and levels of IgG, A, M in the blood, decrease CD4 and thus increased IL-17 and decreased IL-4 . The advisable treatment with Nucleat sodium and Imuret for decrease IL-17 and increase IL-4, production of interferon, stimulation of leucopoiesis and activity factors of nonspecific resistance for prevents pyelonephritis in children with frequent viral respiratory infections and the use of probiotic lactobacilli for normalization of microbiocenosis of the intestine. It was proved levelof enzymuria as a prognostic marker of the activity of the persistent forms of chronic pyelonephritis to determine the tactics of treatment. It was algorithm of diagnosis and differentiated treatment for children with secondary chronic pyelonephritis with ACE inhibitors,probiotics, and immune drugs, differentiated by the trigger factors for relapses, the patient's age, data of a complexly examination developed. Product Description popup.authors Багдасарова І.В. Дріянська В.Є. Калініна Н.А. Король Л.В. Лавренчук О.В. Мигаль Л.Я. Риков О.А. Суслова Г.Д. Фоміна С.П. popup.nrat_date 2020-04-02 Close