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Registration Number

0217U002358, 0114U002064 , R & D reports

Title

To study remote results of Fallot tetralogy total correction during 10-50 years observation period

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Head

Zinkovskiy Myhail Francevich,

Registration Date

07-02-2017

Organization

M.M.Amosov National Institute of Cardio-Vascular Surgery of the Academy of Medical Sciences of Ukraine

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Report on scientific research work (SRW): 142 p., 38 tab., 11 Fig., 4 diagrams, 3 charts, 122 literary sources. The object of study - 4194 patients after radical correction of tetralogy of Fallot in 10-50 years of the observation interval. The object of in-depth study – 427 (10,2%) patients after radical correction of tetralogy of Fallot in different periods of observation. The aim of this work is to improve quality and increase life expectancy for patients with complications that arise in long-term long-term after correction of tetralogy of Fallot. Research method – data analysis examination of patients after radical correction of tetralogy of Fallot for the study of the anatomy, clinical presentation and natural course of the disease, development of surgical tactics and choice of indications for the optimal intervention. The following results are obtained: We have created the program of examination of patients allowed us to obtain all the necessary data concerning clinical and functional status and the anatomical and physiological characteristics abnormalities of the heart in patients after correction of tetralogy of Fallot and to make a choice of one or another form of re-surgery. - To improve the level of pre - and postoperative diagnosis of dysfunction of the ventricles of the heart after correction of tetralogy of Fallot, we have developed and implemented a method for quantitative and qualitative assessment of their anatomy using magnetic resonance imaging and computed tomography with contrast. Studied the factors affecting the negative result of the intervention patients, the comparative assessment of various types of reoperations and proposed their optimal modification. - Certain factors influencing the result of surgical correction are important criteria to predict the outcome of surgical treatment and to choose the adequate tactics of treatment of patients with tetralogy of Fallot. - We are justified indications and contraindications for various kinds of surgical treatment, and repeat surgery, studied the causes of the final progression or occurrence of hemodynamically and clinically relevant anatomical pathology after correction of tetralogy of Fallot. - Obtaining quantitative diagnostic criteria for defining a surgical tactics, as well as improvement of diagnostics methods and repeated surgical interventions led to the reduction of surgical risk and improved the immediate and remote results of treatment of patients with this disease. - We have developed and implemented a method of surgical treatment of obstruction of the excretory tract of the right ventricle during surgical correction of tetralogy of Fallot. - Us proven to reduce complications associated with failure of the valve of the pulmonary artery, which arose in the remote period after correction of tetralogy of Fallot required valve implantation in the pulmonary position that is one step in a full correction of the defect, to improve the quality of life of the patient. - Introduced by us in domestic practice the algorithm of diagnostics and correction of residual congenital and acquired complications after correction of tetralogy of Fallot, which allows you to clearly assess the clinical and geodynamic condition of each patient and to determine the optimal time and kind of re-operation is the key to long-term life with the possibility of social adaptation and preservation of work capacity.

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Ісаєнко В.В.
Бабаджанов К. Б.
Вітовський Р. М.
Горячев А. Г.
Дедкова Т. І.
Дикуха С. О.
Зiньковський М. Ф.
Піщурін О. А.
Сатмарi О. В.

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2020-04-02