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Information × Registration Number 0217U004916, 0112U008232 , R & D reports Title Mechanisms of changes of the mitochondria functional state and structural organization under oxidative stress of various origin. popup.stage_title Head Mankovska Iryna Mikitivna, Registration Date 28-11-2017 Organization Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine popup.description2 It was established the cellular and molecular mechanisms of the mitochondrial morphofunctional changes in rat tissues under oxidative stress modeling and in blood cells of patients with diseases connected with oxidative stress development: the peculiarities of the morphologic and stereometric characteristics of mitochondria, the respiratory chain functioning, the mitochondrial KATP channel activity, pro- and antioxidant reactions, expression of genes and proteins, regulating the mitochondrial oxidative state. It was shown the possibility of these changes correction using pharmacological and non- pharmacological approaches.5481 Product Description popup.authors І.М.Маньковська Бакуновський О.М. Барановська І.О. Болгова Т.В. Братусь Л.В. В.І.Портніченко Гавенаускас Б.Л. Гончар Є.В. Гончар О.О. Древицька Т.І. Дубова М.Г. Колєснікова Є.Е. Лінник О.О. Моісеєнко Є.В. Розова К.В. Серебровська Т.В. Сидоренко А.М. popup.nrat_date 2020-04-02 Close