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Information × Registration Number 0217U004954, 0115U006648 , R & D reports Title Complex pharmacologic studying of novel biologic active compounds of natural and synthetic origin popup.stage_title Head Kresyun Valentin Iosephovich, Registration Date 05-12-2017 Organization Odesa National Medical University popup.description2 The work has revealed: Germicide at intraperitoneal and oral administration in the mice, belongs to practically non-toxic (V class) and low toxicity (class IV) compounds, respectively, while at intraperitoneal and oral administration to the rats, is relatively safe (class VI) and low toxicity (IV class) compounds, respectively. Hercocyte in case of intraperitoneal and oral administration to both species of studied animals belongs to the IV class of compounds (low toxicity). Stamancit after intraperitoneal administration to mice and rats, according to the level of lethal doses refers to practically non-toxic (class V), while after oral administration and stomacitum - after oral and intraperitoneal administration, to class IV compounds (low toxicity). Prolonged administration of coordinated compounds of metals in large doses (1/40 LD50) led to discirculatory changes in the organs of rats, while at the potential therapeutic dose of 1/135 LD50 the morphological disorders were absent. Product Description popup.authors Андронов Дмитро Юрійович Антоненко Катерина Олексіївна Антоненко Петро Борисович Відавська Ганна Георгіївна Годлевський Леонід Семенович Годован Владлена Володимирівна Казанов Анатолій Дмитрович Кресюн Валентин Йосипович Лобашова Катерина Геннадіївна Олійник Ніна Анатоліївна Погоріла Ірина Вікторівна Стречень Сергій Борисович Шемонаєва Катерина Федорівна popup.nrat_date 2020-04-02 Close