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Information × Registration Number 0217U004990, 0115U003633 , R & D reports Title Investigation of mesenchymal stem cells regenerative potency in perinatal pathology of CNS popup.stage_title Head Skibo Galyna Grigorivna, Доктор медичних наук Registration Date 06-12-2017 Organization Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine popup.description2 Using in vivo and in vitro models of periventricular leukomalacia (PVL), we have demonstrated neuroprotective effect of adipose-derived multipotent mesenchymal stromal cells (MMSCs) transplantation. Singenic stereotaxic transplantation of MMSCs decreases of myelin basic protein degradation and reduces the degree of gliosis. Adipose-derived MMSCs have protective effect when they are co-cultivated with the mice brain slices in PVL model in vitro and are able to differentiate into cells of nervous tissue5481 Product Description popup.authors Лушнікова Ірина Василівна Пацева Марина Анатоліївна Скибо Галина Григорівна Цупиков Олег Михайлович popup.nrat_date 2020-04-02 Close