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Information × Registration Number 0217U006904, 0115U001380 , R & D reports Title Creation of a molecular system for delivery of specific proteins into tumor cells based on the study of the interaction of gold nanoparticles with proteins of different classes popup.stage_title Head Kashuba Olena Vitaliivna, Доктор біологічних наук Registration Date 22-12-2017 Organization R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology popup.description2 During the project, it has been shown that GST-fusion protein MRPS18-2 (S18-2) on gold nanoparticles synthesized in the presence of glutathione can be successfully delivered in the cell line of tumors of mammals in a culture. Thus, in the adherent cells of the mammary tumor of MCF7, grafted on tablets in tablets, GST and GST-S18-2 proteins were delivered at high concentrations. Under the action of the GST-S18-2 protein, tumor cells lost the ability to proliferate. The presence of GST-S18-2 protein in tumor cells was demonstrated by fluorescence microscopy. Product Description popup.authors Бучинська Любов Георгіївна Глущенко Надія Миколаївна Кашуба Олена Віталіївна Ковалевська Лариса Миколаївна Юрченко Наталя Петрівна popup.nrat_date 2020-04-02 Close