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Information × Registration Number 0217U007219, 0115U002592 , R & D reports Title Synthesis and study of low molecular weight inhibitors of serine proteinases. popup.stage_title Head Osadchuk Tetyana Volodymyrivna, Registration Date 21-12-2017 Organization Institute of Bioorganic Chemistry and Petrochemistry of National Academy of Sciences of Ukraine popup.description2 The flavonoids were found without positively charged groups in their structure not to be able to interact with the enzyme and inactivate it. The effect on the furin of organic solvents as components of the enzymatic process was studied and the enzyme was found to be the most stable in solutions of DMSO among the organic solvents (DMSO, isopropanol, dioxane, acetone, ethanol). It was shown that the enzyme activity depends on the polarity of the medium.,the hydrophobic contacts and the hydrogen bonds between the enzyme and the ligand, as well as the viscosity or ionic strength of the incubation medium,5481 Product Description popup.authors В.К. Кібірєв О.В. Шибирин popup.nrat_date 2020-04-02 Close