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Information × Registration Number 0218U000207, 0115U003206 , R & D reports Title Development of theory and practice of biocoordination supramolecular chemistry of metalcomplexes of polydentate ligands as a method of decision of medicobiological problems popup.stage_title Head Seifullina Inna Iosifovna, Registration Date 06-02-2018 Organization Odesa I.I.Mechnikov national university.Pervomaisk institute. popup.description2 Complex scientific and technical approach to the synthesis, directed structure formation of 62 low-toxic, with the wide range of pharmacological action, homo- and heterometallic complexes of s-, р-, d-biometals with organic molecules - active substances in well-known drugs and body metabolites, was developed. Their antiviral, cerebroprotective, antifungal, antituberculous, growth stimulating activity was established. Argentum bis(citrato)germinate and cobalt bis(citrato)stannate were proposed and patented as substances of pharmaceutical products, anti-infectious agents, which eliminate the disadvantages of the prototype "tamiflu" and show anti-staphylococcal activity. Iron bis(citrate)germinate was patented as cerebroprotector with closed craniocerebral trauma, which is much more effective, then drug "piracetam" (4 patents of Ukraine). Product Description popup.authors Грекова А.В. Громова М.І. Марцинко О.Е. Масановець Г.М. Пуля А.В. Скороход Л.С. Хитрич М.В. Чебаненко О.А. Шматкова Н.В. popup.nrat_date 2020-04-02 Close