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Information × Registration Number 0218U001464, 0115U000487 , R & D reports Title Investigation of cellular response to electromagnetic and chemical stress factors popup.stage_title Head Shckorbatov U., Registration Date 21-03-2018 Organization Kharkov National University named after V.N. Karazin popup.description2 In experimental objects: human cells, lines and hybrids of Drosophila, seedlings of agricultural plants the effects and manifestation of the cell response to stresses, in particular electromagnetic fields of the microwave range, ionizing radiation, nanoparticles and biologically active substances were investigated. The following methods: study of changes in the frequency of dominant lethal mutations was investigated. in Drosophila, degree of politeny of chromosomes of Drosophila, studying the dynamics of development and vitality of Drosophila, the content of granular heterochromatin (VGG) in human cells, cell viability, and the study of the state of human plasma membrane were applied. The effect of gamma radiation on the duration of life of Drosophila and the degree of politeny of chromosomes, depending on which of the parents was irradiated, and effects of the magnetic and microwave fields on the degree of politeny have been shown. The influence of microwaves on the duration of premiginal development and stability of imago to starvation was revealed. The regularities in the influence of neutron irradiation and gamma irradiation in a complex with microwave and magnetic field on the viability of human cells, depending on the dose of irradiation, the state of chromatin in cell nuclei and the state of cell membranes, are demonstrated. The regularities of the influence of magnetite nanoparticles on the state of chromatin in human cells and regularities of the influence of cerium dioxide nanoparticles on the viability of Drosophila and human cell state were shown. Product Description popup.authors А.Агапій А.Мудрак А.Савенкова В.Страшнюк В.Чешко Д.Мірошник Д.Скоробагатько К.Кузнецов Л.Дика Л.Шайкіна М.Грачова М.Колчигін О.Горенська О.Ніколов С.Біловецька С.Шахбазова Т.Чешко popup.nrat_date 2020-04-02 Close